| QTL Map Information |
|---|
| Chromosome: | 29 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
10.3-10.3 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs69446227 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
Fst | 0.2353 | | P_values | 4.88E-23 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Finnhorses. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina EquineSNP70 BeadChip and GWAS was performed for insulin dysregulation, characteristic of equine metabolic syndrome. A total of 49,287 SNPs were used for analysis. |
| Analysis: | Three different methods were used for association analysis: GWAS in PLINK (-assoc fisher), F(ST) outlier detection based on a hierarchical island model in Arlequin and a Bayesian multinomial-Dirichlet model in BayeScan. Fisher's exact test was used to determine p-values. |
| Software: | PLINK, Arlequin v3.5.2.2, BayeScan v2.1 |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Weckman M J, Karikoski N P, Raekallio M R, Box J R, Kvist L |
| Affiliation: | Department of Equine and Small Animal Sciences, Faculty of Veterinary Medicine, University of Helsinki, P.O. Box 57, FI-00014 Helsinki, Finland |
| Title: | Genome-wide association study suggests genetic candidate loci of insulin dysregulation in Finnhorses |
| Journal: | Veterinary journal (London, England : 1997), 2024, 303: 106063 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
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| Comments: | Detected by Arlequin and BayeScan |
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