Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 1934 Description:

 Trait Information
Trait name: Antibody response to SRBC antigen Vertebrate Trait Ontology: Immune response trait
Reported name: Antibody response to SRBC antigen Product Trait Ontology: n/a
Symbol: ABR-SRBC Clinical Measurement Ontology: Change in antibody titer
 QTL Map Information
Chromosome:3
QTL Peak Location:26 (cM)
QTL Span:9-51 (cM)
3.1-17.7 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":LEI0043
Peak:
Lower, "Significant":MCW0083
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:QTL
Model tested:Mendelian
Test base:Chromosome-wise
Threshold significance level:Suggestive
F_Stat6.20
VARIANCE6.76
P_values<0.05
Dominance effect:1.06
Additive effect:-0.07
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Genetically distinct, highly inbred chicken lines, the Leghorn G-B1 and the MHC-congenic Fayoumi M15.2 and M5.1 lines, were used as parental lines.
     Breeds associated:
    n/a
    Design:At 19 and 23 wk of age, F2 chickens wree intramuscularly injected with SRBC and BA. Blood samples were obtained 7 d after 1st immunization and at 4, 7, 10, 18, 32, and 63 d after 2nd immunization to determine antibody level.
    Analysis:The general linear model tests for associations between individual marker and antibody response paramters were conducted us the JMP program. QTL analysis of 3 autosomal and the Z chromosome was done by using line cross least squares regression.
    Software:JMP and CriMap 2.4 Software
    Notes: 
    Links:Edit

     Reference
    Authors:Zhou H, Li H, Lamont SJ.
    Affiliation:Department of Animal Science, Iowa State University, Ames, Iowa 50011-3150, USA.
    Title:Genetic markers associated with antibody response kinetics in adult chickens.
    Journal:Poultry Sci, 2003, 82(5):699-708
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #12762390
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  • Cite this Data:

    Animal QTLdb: QTL1934 was published in 2003, and was curated into QTLdb on 2010-06-22. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:1934

     

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