| QTL Map Information |
|---|
| Chromosome: | 4 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
32.3-32.3 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs13513973 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 1.38E-5 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | ARHGAP10 (Rho GTPase activating protein 10) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Birds were commercial chickens from the Hy-Line W-36 White Leghorn layer variety. Samples were obtained following two different HPAI outbreaks in multiple commercial layer facilities in two countries (US and and Mexico). |
| Breeds associated:
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| Design: | Birds were genotyped using the Affymetrix Axiom 600K chicken SNP chip and analyzed for SNP association with highly pathogenic avian influenza (HPAI) infection survival. A total of 348,161 (Mexico) or 340,791 (US) SNPs were used for analysis. |
| Analysis: | Logistic regression, mixed models, and a Bayesian variable selection GWAS approach were used. |
| Software: | PLINK, GenSel, ASReml, Beagle, Haploview |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Drobik-Czwarno W, Wolc A, Fulton J E, Arango J, Jankowski T, O'Sullivan N P, Dekkers J C M |
| Affiliation: | Department of Animal Science, Iowa State University, Ames, IA, USA |
| Title: | Identifying the genetic basis for resistance to avian influenza in commercial egg layer chickens |
| Journal: | Animal : an international journal of animal bioscience, 2019, 12(7): 1363-1371 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
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| Comments: | Iowa/H5N2 outbreak |
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