| QTL Map Information |
|---|
| Chromosome: | 12 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
3.1-3.1 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs734271895 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Experiment-wise |
| Threshold significance level: | Significant |
 |
FDR | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | ALAS1 (5'-aminolevulinate synthase 1) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
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| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Chickens were derived from a Rhode Island Red line that was bidirectionally selected for six generations according to eggshell brownness, resulting in experimental lines with light brown and dark brown eggshells. |
| Breeds associated:
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| Design: | Following comparative transcriptome and RT-qPCR to identify genes of interest, SNPs in the ALAS1 gene were analyzed for association with eggshell brownness. |
| Analysis: | Case-control association analysis was performed using PLINK. |
| Software: | GATK v4-4.2.3.0, Beagle v5.2, PLINK v1.90, R software v4.1.1 |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Yang J, Mao Z, Wang X, Zhuang J, Gong S, Gao Z, Xu G, Yang N, Sun C |
| Affiliation: | National Engineering Laboratory for Animal Breeding and Key Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affairs, China Agricultural University, Beijing, 100193, China |
| Title: | Identification of crucial genes and metabolites regulating the eggshell brownness in chicken |
| Journal: | BMC Genomics, 2022, 23(1): 761 |
| Links: |
PubMed | Abstract | List all data
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