| QTL Map Information |
|---|
| Chromosome: | 11 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
|
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | ITGB4 (integrin subunit beta 4) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Mouton Vendéen sheep. |
| Breeds associated:
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| Design: | Whole-genome sequencing was performed on lambs affected and unaffected by epidermolysis bullosa to identify candidate mutations. |
| Analysis: | Variant analysis was performed for 13 candidate genes fitting with the mutation segregation hypothesis. |
| Software: | GATK |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Fabre S, Chantepie L, Plisson-Petit F, Sarry J, Woloszyn F, Genet C, Drouilhet L, Tosser-Klopp G |
| Affiliation: | GenPhySE, INRAE, INPT, ENVT, Université de Toulouse, 31326, Castanet-Tolosan Cedex, France |
| Title: | A novel homozygous nonsense mutation in ITGB4 gene causes epidermolysis bullosa in Mouton Vendéen sheep |
| Journal: | Animal Genetics, 2021, 52(1): 138-139 |
| Links: |
PubMed | Abstract | List all data
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