| QTL Map Information |
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| Chromosome: | 3 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
94.5-94.5 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs414400434 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 2.42E-6 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | EXOC6B (exocyst complex component 6B) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were Columbia, Polypay, and Rambouiillet ewes. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina OvineSNP50 BeadChip or Ovine Infinium HD SNP BeadChip. Lower-density genotypes were imputed to HD, and GWAS was performed for monocyte count. A total of 542,255 SNPs were used for analysis. |
| Analysis: | A single-locus mixed linear model was used for GWAS. |
| Software: | PLINK v1.9, R software, Beagle v5.1, SNP & Variation Suite v.8.9.0, EMMAX |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Oliveira RD, Mousel MR, Gonzalez MV, Durfee CJ, Davenport KM, Murdoch BM, Taylor JB, Neibergs HL, White SN |
| Affiliation: | Department of Veterinary Microbiology & Pathology, Washington State University, Pullman, Washington, United States of America |
| Title: | A high-density genome-wide association with absolute blood monocyte count in domestic sheep identifies novel loci |
| Journal: | PLoS One, 2022, 17: e0266748 |
| Links: |
PubMed | Abstract | List all data
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