| QTL Map Information |
|---|
| Chromosome: | 3 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
201.8-201.8 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs406747332 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | - |
| Test base: | - |
| Threshold significance level: | Significant |
 |
Fst | 0.196 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | GRIN2B (glutamate ionotropic receptor NMDA type subunit 2B) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were VAlle del Belice sheep. |
| Breeds associated:
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| Design: | Animals were genotyped using using the Illumna Ovine 600K BeadChip, and GWAS was performed for susceptibility to small ruminant lentivrus (Visna/Maedi virus). A total of 353,100 SNPs were used for analysis. |
| Analysis: | Univariate case/control GWAS was performed using the log-additive genetic model. Case/control analyses were also performed using Fisher's exact test and F(ST). |
| Software: | PLINK v1.9, SNPassoc in R, GenABEL |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Riggio S, Tolone M, Sottile G, Tumino S, Portolano B, Sutera AM, Sardina MT, Cesarani A, Mastrangelo S |
| Affiliation: | Dipartimento Scienze Agrarie, Alimentari e Forestali, University of Palermo, Palermo, Italy |
| Title: | A high-density genome-wide approach reveals novel genetic markers linked to small ruminant lentivirus susceptibility in sheep |
| Journal: | Frontiers in Genetics, 2024, 15: 1376883 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
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| Comments: | F(ST) analysis |
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