Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

Running...
Version: Enrich S: beta v0.8
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Data:

Number of defects traits:7
Number of QTL / associations found:356
Number of chromosomes where QTL / associations are found:19

Chi-squared (χ2) test: are defects traits over-represented on some chromosomes?

Chromosomes Total χ2 df p-values FDR * Size of χ2
Chromosome X8.38264180.97237929.999838e-01
Chromosome 18.38264180.97237929.999838e-01
Chromosome 247.39385180.00018517003.518230e-04
Chromosome 360.60733181.631604e-066.200095e-06
Chromosome 412.29557180.8316089.999838e-01
Chromosome 522.36297180.21626832.935070e-01
Chromosome 656.18319188.338e-061.980275e-05
Chromosome 747.39385180.00018517003.518230e-04
Chromosome 81182.63264185.882056e-2401.117591e-238
Chromosome 98.38264180.97237929.999838e-01
Chromosome 1028.51744180.054605037.980735e-02
Chromosome 1170.49777183.721941e-081.767922e-07
Chromosome 1235.41916180.0083674051.324839e-02
Chromosome 1356.18319188.338e-061.980275e-05
Chromosome 1456.18319188.338e-061.980275e-05
Chromosome 152.79832180.99998389.999838e-01
Chromosome 1643.06799180.00078271551.351963e-03
Chromosome 1770.49777183.721941e-081.767922e-07
Chromosome 1892.52026185.079768e-124.825780e-11

Chi-squared (χ2) test: Which of the 7 defects traits are over-represented in the QTLdb

Traits Total χ2 df p-values FDR * Size of χ2
Anal atresia 90.82101 6 2.045844e-17 7.160454e-17
Osteochondrosis score 32.13301 6 1.538697e-05 2.154176e-05
Scrotal/inguinal hernia 108.50148 6 4.197507e-21 2.938255e-20
Spinal curvature 48.20584 6 1.074835e-08 1.880961e-08
Splay leg 24.18027 6 0.0004838453 5.644862e-04
Umbilical hernia 56.93182 6 1.885914e-10 4.400466e-10
rhinitis 19.23391 6 0.003786303 3.786303e-03

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data Chi'Square Test Fisher's Exact Test
Number of chrom.:19 χ2=1909.702410
Number of traits:7 df=108
Number of QTLs:356 p-value=0

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.

 

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