Release 56
(Apr 24, 2025)

Reference # 10816979 Details:

Authors:Andersson-Eklund L, Uhlhorn H, Lundeheim N, Dalin G, Andersson L.
Affiliation:Department of Animal Breeding and Genetics, Swedish University of AgriculturalSciences, Uppsala. Contact: lena.andersson-eklund@hgen.slu.se
Title:Mapping quantitative trait loci for principal components of bone measurementsand osteochondrosis scores in a wild boar x large white intercross.
Journal:Genet Res., 2000, 75(2):223-30 DOI: 10.1017/s0016672399004371
Abstract:

Data on osteochondrosis and femur dimensions from 195 F2 pigs from a wild boar xLarge White intercross were analysed with the aim of detecting quantitativetrait loci (QTLs) for normal and disturbed bone formation. The information fromnumerous recorded traits was summarized by principal component analysis andanalysed by least-squares interval mapping. An increase in the proportion ofwild boar alleles across the genome increased length versus width of femur andreduced the prevalence of osteochondrosis. The presence of QTLs with an impacton femur dimensions was indicated on chromosomes 2, 4, 16 and 17 and onosteochondrosis on chromosomes 5, 13 and 15. A substantial effect of thechromosome 5 QTL calls for further studies within commercial populations toevaluate whether marker-assisted selection could be used to reduce theprevalence of osteochondrosis.

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