Release 56
(Apr 24, 2025)

QTL 17928 Description:

 Trait Information
Trait name: Bone mineral density Vertebrate Trait Ontology: Bone mineral mass
Reported name: Bone mineral density Product Trait Ontology: n/a
Symbol: BMD Clinical Measurement Ontology: Bone mineral density
 QTL Map Information
Chromosome:9
QTL Peak Location:37.7 (cM)
QTL Span:20.16-20.17 (cM)
14.5-14.5 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values<0.05
Dominance effect:0.0039
Additive effect:0.016
Associated Gene:MMP3 (matrix metallopeptidase 3 (stromelysin 1, progelatinase))
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Duroc x Pietrain cross-bred pigs or commercial animals from Large White x Landrace dam lines and Large White x Duroc sire lines.
     Breeds associated:
    Design:Animals were genotyped for one SNP in each of MMP3, TGFB1, and COL10A1 and analyzed for leg weakness-related traits.
    Analysis:The general linear model procedure was used.
    Software:SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Laenoi W, Rangkasenee N, Uddin MJ, Cinar MU, Phatsara C, Tesfaye D, Scholz AM, Tholen E, Looft C, Mielenz M, Sauerwein H, Wimmer
    Affiliation:Institute of Animal Science, Animal Breeding and Husbandry Group, University of Bonn, Endenicher allee 15, 53115, Bonn, Germany
    Title:Association and expression study of MMP3, TGFβ1 and COL10A1 as candidate genes for leg weakness-related traits in pigs
    Journal:Mol Biol Rep, 2012, 39(4):3893-901
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:g.158C>T
    User inputs on reference #21739142
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  • Cite this Data:

    Animal QTLdb: QTL17928 was published in 2012, and was curated into QTLdb on 2012-09-04. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:17928

     

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