| QTL Map Information |
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| Chromosome: | 14 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
59.6-59.6 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs340675701 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Experiment-wise |
| Threshold significance level: | Significant |
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P_values | 0.046 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | CAPN9 (calpain 9) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
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| QTL Experiment in Brief |
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| Animals: | Animals were from two cohorts of crossbred commercial pigs. Panel 1 originated from a cross between a DunBred (Landrace x Yorkshire) maternal hybrid line and Landrace or Duroc paternal lines. Panel 2 was the offspring of a cross between a maternal Camborough+ hybrid line (itself a cross of Large White x Duroc, and a paternal line, a cross between British Large White and Pietrain. |
| Breeds associated:
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| Design: | Animals were genotyped for SNPs in the CAPN9, OSM, and ITGAM genes, and association analysis was performed for umbilical hernia. |
| Analysis: | An odds ratio test was performed to determine significant differences between SNP allele frequencies comparing umbilical hernia cases and controls. Logistic regression was used to analyze haplotype effects. |
| Software: | MedCalc, R software (SNPassoc v2.0-2, haplo.stats v1.8.7, haplo.glm) |
| Notes: | |
| Links: | Edit |
| Reference |
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| Authors: | Wozniak J, Loba W, Iskrzak P, Pszczola M, Wojtczak J, Switonski M, Nowacka-Woszuk J |
| Affiliation: | Department of Genetics and Animal Breeding, Poznan University of Life Sciences, Poznan, Poland |
| Title: | A confirmed association between DNA variants in CAPN9, OSM, and ITGAM candidate genes and the risk of umbilical hernia in pigs |
| Journal: | Animal Genetics, 2023, 54(3): 307-314 |
| Links: |
PubMed | Abstract | List all data
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