Release 56
(Apr 24, 2025)

QTL 31208 Description:

 Trait Information
Trait name: Cholesterol level Vertebrate Trait Ontology: Blood cholesterol amount
Reported name: Cholesterol level Product Trait Ontology: n/a
Symbol: CHOLS Clinical Measurement Ontology: Blood total cholesterol level
 QTL Map Information
Chromosome:2
QTL Peak Location:57.0 (cM)
QTL Span:40.09-40.10 (cM)
27.7-27.8 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
VARIANCE7.00
P_values1.06E-9
Dominance effect:n/a
Additive effect:n/a
Associated Gene:LDLR (low density lipoprotein receptor)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from three pig populations: White Duroc x Erhualian F2, Sutai, and Duroc x Landrace x Large White.
     Breeds associated:
    Design:Animals were genotyped using the Illumina PorcineSNP60 BeadChip and/or for two SNPs in LDLR and analyzed for serum LDL and total cholesterol levels.
    Analysis:A linear mixed model was used.
    Software:Haploview, Glascow, SAS, R software, PLINK
    Notes: 
    Links:Edit

     Reference
    Authors:Zeng Z, Chen R, Liu C, Yang H, Chen C, Huang L
    Affiliation:Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China, Jiangxi Agricultural University, Nanchang, 330045, China
    Title:Evaluation of the causality of the low-density lipoprotein receptor gene (LDLR) for serum lipids in pigs
    Journal:Animal genetics, 2014, 45(5): 665-73
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #24954195
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  • Cite this Data:

    Animal QTLdb: QTL31208 was published in 2014, and was curated into QTLdb on 2014-10-30. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:31208

     

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