Release 56
(Apr 24, 2025)

QTL 4887 Description:

 Trait Information
Trait name: Age at puberty Vertebrate Trait Ontology: Onset of fertility
Reported name: Age at puberty Product Trait Ontology: n/a
Symbol: AGEP Clinical Measurement Ontology: Age of puberty
 QTL Map Information
Chromosome:10
QTL Peak Location:129.23 (cM)
QTL Span:122-128 (cM)
69.3-72.2 (Mbp)
Upper, "Suggestive":SWR67
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":SW2067
Marker type:Microsatellites
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Suggestive
P_values0.093
Dominance effect:n/a
Additive effect:n/a
Associated Gene:AKR1C4 (aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4))
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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    •  QTL Experiment in Brief
    Animals:Animals were from reciprocal backcrosses of Meishan x White composite (Chester White, Landrace, Large White, Yorkshire). The half-Meishan animals were crossed with a Landrace-Large White composite.
     Breeds associated:
    n/a
    Design:A cluster of 5 aldo-keto reductase genes (AKR1C) was mapped to chromosome 10q. Animals were genotyped for twelve SNPs in the genes of the cluster.
    Analysis:Age at puberty, nipple number, and ovulation rate were analyzed for association with genotypes by MTDFREML using an animal model.
    Software:CRIMAP
    Notes: 
    Links:Edit

     Reference
    Authors:Nonneman, Dan J; Wise, Tommy H; Ford, J Joe; Kuehn, Larry A; Rohrer, Gary A
    Affiliation:USDA-ARS, US Meat Animal Research Center, Clay Center, Nebraska, 68933, USA
    Title:Characterization of the aldo-keto reductase 1C gene cluster on pig chromosome 10: possible associations with reproductive traits.
    Journal:BMC veterinary research, 2006, (2): 28
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #16970816
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    • Cite this Data:

    Animal QTLdb: QTL4887 was published in 2006, and was curated into QTLdb on 2012-07-31. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:4887

     

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