Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 7585 Description:

 Trait Information
Trait name: Melanoma susceptibility Vertebrate Trait Ontology: n/a
Reported name: Melanoma susceptibility Product Trait Ontology: n/a
Symbol: MELAN Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:1
QTL Peak Location:78.0 (cM)
QTL Span:76.92-77.08 (cM)
157.5-158.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":SW962
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:QTL
Model tested:Mendelian
Test base:Chromosome-wise
Threshold significance level:Significant
P_values<0.01
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

User inputs on QTL #7585
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  •  QTL Experiment in Brief
    Animals:Animals from the melanoma-susceptible MeLiM strain (derived from Hormel, Gottingen, Canadian Landrace, Cornwall, Large White, and Vietnamese) were crossed with Duroc.
     Breeds associated:
    n/a
    Design:Animals were genotyped for 153 microsatellite markers and analyzed for their susceptibility to cutaneous melanoma.
    Analysis:Interval mapping using maximum likelihood was used.
    Software:SAS, CRIMAP
    Notes: 
    Links:Edit

     Reference
    Authors:Du, Z-Q; Vincent-Naulleau, S; Gilbert, H; Vignoles, F; Crechet, F; Shimogiri, T; Yasue, H; Leplat, J-J; Bouet, S; Gruand, J; Hor
    Affiliation:CEA-INRA, Laboratoire de Rabiobiologie et d'Etude du Genome, INRA Jouy-en-Josas, F-78352 France
    Title:Detection of novel quantitative trait loci for cutaneous melanoma by genome-wide scan in the MeLiM swine model.
    Journal:International journal of cancer, 2007, 120 (2): 303-20
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Number of aggressive melanomas ("Malignant A")
    User inputs on reference #17066441
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  • Cite this Data:

    Animal QTLdb: QTL7585 was published in 2007, and was curated into QTLdb on 2009-09-09. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:7585

     

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