| QTL Map Information |
|---|
| Chromosome: | 6 |
| QTL Peak Location: | 4.5 (cM) |
| QTL Span: | 7.21-7.27 (cM)
2.3-7.6 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Chromosome-wise |
| Threshold significance level: | Significant |
 |
P_values | 0.04 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | MC1R (melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)) |
| Cis/Trans acting type: |  |
| Links:
NCBI GeneDB | Edit |
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals from the melanoma-susceptible MeLiM strain (derived from Hormel, Gottingen, Canadian Landrace, Cornwall, Large White, and Vietnamese) were crossed with Duroc. |
| Breeds associated:
n/a
|
| Design: | Animals were genotyped for 153 microsatellite markers and analyzed for their susceptibility to cutaneous melanoma. |
| Analysis: | Interval mapping using maximum likelihood was used. |
| Software: | SAS, CRIMAP |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Du, Z-Q; Vincent-Naulleau, S; Gilbert, H; Vignoles, F; Crechet, F; Shimogiri, T; Yasue, H; Leplat, J-J; Bouet, S; Gruand, J; Hor |
| Affiliation: | CEA-INRA, Laboratoire de Rabiobiologie et d'Etude du Genome, INRA Jouy-en-Josas, F-78352 France |
| Title: | Detection of novel quantitative trait loci for cutaneous melanoma by genome-wide scan in the MeLiM swine model. |
| Journal: | International journal of cancer, 2007, 120 (2): 303-20 |
| Links: |
PubMed | Abstract | List all data
| Edit |
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