From listmaster animalgenome.org Mon May 22 09:06:49 2023
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From: "Calus, Mario" <mario.caluswur.nl>
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To: Members of AnGenMap <angenmapanimalgenome.org>
Subject: Two PhD positions at Wageningen University: Genetic
analysis of recombination events and their
contribution to genetic variance
Date: Mon, 22 May 2023 09:06:49 -0500
We are looking for two enthusiastic PhD candidates, with a keen interest in
animal breeding and genetics, analyzing genomic and phenotypic data, and
understanding the origin of genetic variation.
Do you have a background in animal or plant breeding, quantitative genetics,
genomic data analysis, or another quantitative field? Then you are the
candidate we are looking for!
The PhD candidates will be employed at a newly funded NWO-AES project
CrossOver: "Utilizing the full potential of crossovers in animal breeding".
The CrossOver project aims to empirically quantify the contribution of
crossover counts to additive genetic variance, and the potential of selecting
explicitly for crossover counts in animal breeding programs.
Individuals differ in the number of crossovers that they transmit to their
offspring, and the crossover count is at least partly heritable. It is well
known that crossovers contribute to genetic variation that is exploited in
selection in species that reproduce sexually. This contribution is, however,
not yet empirically quantified. The CrossOver project aims to empirically
quantify this contribution based on data from pigs. To do this, models will
be developed and validated within the project.
You will be involved in:
• Developing, validating and applying new methodology to estimate the
contribution of crossover counts to additive genetic variance.
• Detecting crossover events in a large pig dataset.
• Empirically investigating the relationship between the number of
crossovers and other traits that have been under ongoing selection based on
a large pig dataset from a routine breeding program.
• Estimating the effect of recent selection on the crossover count and
predicting the effect of future selection on crossover counts in pigs
Candidates should have:
• A Master's degree in a relevant quantitative field (Quantitative genetics,
Statistical genetics, Statistics, Bioinformatics, or something related).
• A strong interest in fundamental and applied research;
• A strong interest in animal genetics;
• A strong interest in statistical genetic analysis;
• Some experience with computer scripting (e.g. bash, Python, Linux, R);
• Be creative and innovative;
• Good organisational and communication skills in English (written and
spoken), as well as a; proven ability to collaborate with others;
• Willingness to travel internationally, to attend international project
meetings and conferences and visit other institutes. In the first year the
candidates will spend some time at the University of Liege (Belgium) to
collaborate with Dr. Tom Druet.
We only consider applications made through our online system. The link to
apply, as well as more information about the PhD positions, can be found
here: PhD position: Genetic analysis of recombination events and their
contribution to genetic variance - WUR
Closing date is 7th June 2023. Submit your application online through the
link above. Please provide the requested details and upload both a motivation
letter and CV.
Best regards,
Yvonne Wientjes & Mario Calus
With kind regards,
Dr. ir. M.P.L. (Mario) Calus
Associate Professor
Wageningen University & Research,
Animal Breeding and Genomics (ABG)
Mailing address: P.O. Box 338, 6700 AH Wageningen, The Netherlands
Visiting address: Droevendaalsesteeg 1, 6708 PB Wageningen, The Netherlands
T +31 317 480501 (also mobile)
E mario.caluswur.nl
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