Identification of important genes: QTL linkage analysis

10/26/00


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Table of Contents

Identification of important genes: QTL linkage analysis

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Marker Association

Marker Association

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Finding Trait Genes Comparative positional candidate gene strategy

High Resolution QTL Mapping

Finding Trait Genes Comparative positional candidate gene strategy

Interval Mapping for Early Weight and Growth Rate at Different Stages (pooled data)

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Pig Genome Mapping QTL

Beef QTL Results

Beef QTL Results

Beef QTL Results

Chicken Genome Mapping QTL

Dairy QTL Results

Question: How do we find these QTL? Answer: Interval analysis

What is the theory

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Linkage between loci

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Processes that create Population-wide Linkage Disequilibrium

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Marker association - Problem

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Simulation example

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Summary of simulation

Author: jdekkers

Email: mfrothsc@iastate.edu

Home Page: /edu/QTL/rothschild/