ANNUAL PROGRESS REPORT

NATIONAL RESEARCH SUPPORT PROJECT - NRSP-8

Year Ending 2002

Preliminary Information-Not for Publication

Lee Alexander

University of Minnesota

College of Veterinary Medicine

 

I. PROJECT TITLE:

National Animal Genome Research Program (NAGRP)

 

II. COOPERATING AGENCIES AND PRINCIPAL LEADERS:

University of Minnesota Personnel

Leeson Alexander, Assistant Professor

Collaborators at other Institutions

III. NATURE OF WORK AND PRINCIPAL RESULTS OF YEAR:

Objective: 1. Develop high-resolution comparative genome maps aligned across species that link agricultural animal maps to those of the human and mouse genomes.

 

Objective: 2. Increase marker density of existing linkage maps used in QTL mapping and integrate them with physical maps of animal chromosomes.

In the period that the project has been underway we have 1770 primer pairs developed and have mapped 771 new microsatellite markers on the IMpRH panel.

IV. APPLICATION OF FINDINGS:

The mapping these new porcine microsatellites is increasing the density of markers on the 7000 rad IMpRH panel.

 

V. WORK PLANNED FOR NEXT YEAR:

A. We will continue to map markers on the 7000 rad IMpRH panel.

 

VI. PUBLICATIONS:

Korwin-Kossakowska, A. , K. M. Reed, C. Pelak, E. Krause, L. Morrison, and L. J. Alexander. 2002 Radiation hybrid mapping of 118 new porcine microsatellites. Anim. Genet. 33: 220-223.

. Krause, E., Morrison, L. , Reed, K M. and Alexander, L J., 2002 Radiation hybrid mapping of 273 previously unreported porcine microsatellites. Anim. Genet. 33; 477-485.